Ciplin Ds 800 Mg/160 Mg

Ciplin Ds 800 Mg/160 Mg and 125 Mg tablets are prescription-only medicine. It is a combination of antibiotics which are penicillin-type and are used to treat bacterial infections. The two active ingredients of this tablet are Sulfamethoxazole and Trimethoprim. Its generic name is Sulfamethoxazole +Trimethoprim and is sold under brand name Septra DS. It is available in various strengths, including 800 Mg and 160 mg. It is a product of Cipla Ltd.

When are Ciplin Ds 800 Mg/160 Mg tablets used?

Ciplin Ds 800 Mg/160 Mg and 160 Mg tablets are used for the treatment of various common bacterial infections of the ear, nose, throat, genitourinary tract, soft tissue and skin. This medication is used for the treatment of infections caused by gram-negative and gram-positive bacterias, including Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus ducreyi, Nocardia, Streptococcus faecalis, E.coli, Pneumocystis jiroveci, Haemophilus influenzae, Klebsiella granulomatis, etc. This medication is also used for the treatment of tonsillitis, pneumonia, bronchitis, and gonorrhoea. It is also used to treat and prevent toxoplasmosis. It is also considered effective in some bacterial bone and joint infections, especially dental infections. Ciplin DS 800

What are the significant Side Effects of Ciplin Ds 800 Mg/160 Mg tablets?

You should be aware of these common side effects before you buy Ciplin Ds 800 Mg/160 Mg:

• Stomach upset
• Nausea and Vomiting
• Diarrhea
• Itching and skin rash
• Black or tarry stools
• Headache
• Shortness of breath
• Unusual bleeding or bruising
• Yellow eyes or skin

What is the usual dosage of Ciplin Ds 800 Mg/160 Mg tablets as recommended?

• Dosage: The dosage should be prescribed by your doctor according to your specific condition, age and weight. Do not take extra or reduce the prescribed dosage without consulting your doctor. Complete the full course of the medicine even if you don’t see any improvements or feel better already.

Ciplin DS 800 and 160 Mg contains a fixed combination product containing sulfamethoxazole and trimethoprim in 5:1 ratio.

The commonly prescribed dosage you should know before you buy Ciplin Ds 800 Mg/160 Mg:

• For Adults: The dose is two tablets every 12 hours for a period of 10 to 14 days.

• For Children: The dose is 8 mg/kg of trimethoprim and 40 mg/kg of sulfamethoxazole daily in 2 divided doses every 12 hours.
• Missed Dose: Take the missed dosage immediately as you remember it. If you recall near to the time of your next dose, do not take the double dose and stick to your regular schedule.
• Overdose: Contact a nearby doctor as soon as possible if you experience signs like stomach pains, vomiting, diarrhoea or convulsions.

How Do Ciplin Ds 800 Mg/160 Mg tablets Work?

Ciplin DS Tablet contains a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. It has a broad spectrum of action. These antibiotics prevent the growth of the bacteria by inhibiting certain steps in the biosynthesis of purines and therefore nucleic acids which is necessary for DNA replication.

Both Sulfamethoxazole and Trimethoprim act as a competitive inhibitor of dihydropteroate synthetase, a bacterial enzyme. These two compounds hinder the combination of Aminobenzoic acid (PABA) and dihydropteroate synthetase. For the synthesis of folic acid to take place, this inhibition reaction is necessary. As a result of this, the bacteria are unable to produce folic acid, which is essential for its multiplication.

Warnings and Precautions

Do not buy Ciplin Ds 800 Mg/160 Mg online if you are pregnant or breastfeeding. Consult your doctor for close alternatives or adjusted dosage if cannot be avoided.

You are not recommended to use this medication if you have suffered from:

Allergic Reaction

If you suffer from or have a history of any allergy to Sulfamethoxazole and Trimethoprim or any antibiotics in general, do not to take this medication unless you consult your doctor for the appropriate dosage or replacements. Ciplin Ds 800 Mg/160 Mg and 160 Mg is likely to cause moderate to a severe allergic reaction.

G6PD deficiency

You are not recommended to take this drug if you are suffering from G6PD deficiency. It increases the risk of worsening of the pre-existing condition. Ask your doctor for replacements or close alternatives.

Colitis

Patients having a history of or suffering from gastrointestinal diseases, particularly colitis, should use Ciplin Ds 800 Mg/160 Mg with extra caution. It may worsen the patient's condition. Report any incidence of severe diarrhoea, abdominal pain, blood in stools, etc. to the doctor immediately.

Hematologic Toxicities

It is strongly recommended that patients with a known history of blood disorders or bone marrow disorders should consult a doctor before committing to this medication. There is a chance of increased risk of severe side effects like clotting disorders, methemoglobinemia, thrombocytopenia, aplastic anaemia, or hemolytic anaemia

Folate deficiency

Patients with malabsorption syndrome or patients with megaloblastic anaemia caused by folate deficiency and who are on other folate depleting medications should take extra precautions while taking Ciplin Ds 800 Mg/160 Mg. Ask your doctor for replacements or close alternatives.

Common Substitutes of Ciplin Ds 800 Mg/160 Mg tablets

• Welprim DS Tablet
• Ridprim DS Tablet
• Chemotrin Forte 800 Mg/160 Mg Tablet
• Aanprim DS 800 Mg/160 Mg Tablet
• Utibact DS 800 Mg/160 Mg Tablet
• Rizol DS 800 Mg/160 Mg Tablet
• Jolltrim-DS Tablet
• Sumetrol DS 800 Mg/160 Mg Tablet

Ciplin Ds 800 Mg/160 Mg tablets interactions with Other Drugs

You are not advised to buy Ciplin DS 160 Mg if you are taking any of the below-mentioned medications. Consumption of Ciplin DS 800/160 Mg tablets along with these drugs, can cause a surge in side effects or can worsen your existing condition.

• Angiotensin Receptor Blockers (ARB)
• Phenytoin
• Methotrexate
• Estradiol
• Warfarin
• Metformin

Frequently Asked Questions:

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